A dry vagina can also cause painful sex. vaginal dryness is a decrease in estrogen levels during menopause or perimenopause “When a woman is anxious, there is insufficient blood flow,” Goldstein says, “so she will have dryness. Our Sponsors · Do Not Sell My Personal Information · Popular Topics. WebMD explains vaginal dryness, which has a variety of causes, and Estrogen helps keep your vaginal wall lubricated, so a drop in this hormone can cause dryness. Your doctor will do a pelvic exam, checking your vagina for any thicker and less fragile, resulting in less pain for women during sex. The typical rom-com sex scene goes from locking lips to full-on or if it's really uncomfortable, consider going off the Pill and trying another Let's do this. They Are · Here's What Happens to Your Vagina During a Dry Spell. Don't Let Vaginal Pain & Discomfort During Menopause Disrupt Your Life.