Example (Adjective): “After coming out, I researched lesbian women from our history.” No one knows for sure what makes a person straight, gay, lesbian, or even. Lesbian definition is - of, relating to, or characterized by sexual or romantic in the examples do not represent the opinion of Merriam-Webster or its editors. Wiktionary( / 2 votes)Rate this definition: lesbian(Noun). A homosexual female, a female who is sexually or romantically attracted to other females. Etymology. A lesbian is a woman who is romantically, emotionally, and/or sexually attracted to other women. This term is also known as “gay” or “gay.